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An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics |
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| Authors: | A Tura S Sbrignadello E Succurro L Groop G Sesti G Pacini |
| Institution: | 1. Metabolic Unit, ISIB-CNR, Corso Stati Uniti, 4, 35127, Padova, Italy 2. Department of Experimental and Clinical Medicine, University Magna Gr?cia of Catanzaro, Catanzaro, Italy 3. Lund University Diabetes Centre, Lund University, Malm?, Sweden 4. Research Program for Molecular Medicine, Helsinki University, Helsinki, Finland |
| Abstract: | Aims/hypothesisMinimal model analysis for insulin sensitivity has been validated against the glucose clamp and is an accepted method for estimating insulin sensitivity from IVGTT. However minimal model analysis requires a 3 h test and relevant expertise to run the mathematical model. The aim of this study was to suggest a simple predictor of minimal model analysis index using only 1 h IVGTT. |
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