计算的检验项目室内质量控制方法研究

目的探讨计算的检验项目室内质量控制方法。方法以低密度脂蛋白胆固醇(LDL-C)为例使用泰勒级数展开和其他的公式获得计算的检测项目的均值和标准差,绘制Levey-Jennings质控图并使用Westgard规则对质控结果分析。结果对LDL-C等计算的检验项目检测使用修改后的质控图并用Westgard规则进行分析提高了检验结果的可靠性。结论只对直接测定的项目进行质控是不够的,运用质控图和质控规则对计算的检验项目进行室内质量控制可以提高结果的可靠性,是整个检验医学质量管理的一部分。

Research on the method of internal quality control for calculated laboratory tests

Objective To investigate the method of internal quality control for calculated laboratory tests.Methods A method was developed using a Taylor series expansion and alternative equations to obtain the mean value and standard deviation of calculated laboratory tests as low density lipoprotein cholesterol（LDL-C） for example,and then Levey-Jennings charts were printed.The results were analyzed by Westgard multirules.Results The preparation of Levey-Jennings charts for LDL-C（and other calculated laboratory tests） and the application of Westgard multirules to calculate LDL-C（and other calculated laboratory tests） could increase the reliability of the results of the calculated laboratory tests.Conclusions Checking the reliability of only the measured tests by internal quality control before reporting patient results may be inadequate.Applying the quality control charts and Westgard multirules to calculate tests as a part of total quality management will increase the reliability of test results.