New serological assay for detection of putative Helicobacter pylori virulence factors |
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Authors: | Park Chang-Young Cho Yong-Kyun Kodama Tadashi El-Zimaity Hala M T Osato Michael S Graham David Y Yamaoka Yoshio |
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Affiliation: | Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA. |
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Abstract: | We evaluated a new immunoblot assay (Helicoblot 2.1) for Helicobacter pylori infection and CagA and VacA status by using serum samples from 222 patients. The test accurately detected H. pylori infection and VacA status, but improvements in the interpretation criteria are required before it can be recommended for determination of CagA status. |
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