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The McCAVE Trial: Vanucizumab plus mFOLFOX-6 Versus Bevacizumab plus mFOLFOX-6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC)
Authors:Johanna C. Bendell  Tamara Sauri  Antonio Cubillo Gracián  Rafael Alvarez  Carlos López-López  Pilar García-Alfonso  Maen Hussein  Maria-Luisa Limon Miron  Andrés Cervantes  Clara Montagut  Cristina Santos Vivas  Alberto Bessudo  Patricia Plezia  Veerle Moons  Johannes Andel  Jaafar Bennouna  Andre van der Westhuizen  Leslie Samuel  Simona Rossomanno  Christophe Boetsch  Angelika Lahr  Izolda Franjkovic  Florian Heil  Katharina Lechner  Oliver Krieter  Herbert Hurwitz  for the McCAVE Study Group
Affiliation:1. Sarah Cannon Research Institute and Tennessee Oncology, Nashville, Tennessee, USA;2. Vall d‘Hebron University Hospital, Barcelona, Spain;3. Centro Integral Oncológico Clara Campal, Hospital Madrid Norte Sanchinarro, Madrid, Spain;4. Marqués de Valdecilla University Hospital, Santander, Spain;5. Hospital Universitario Gregorio Maranon, Madrid, Spain;6. Florida Cancer Specialists, Leesburg, Florida, USA;7. Hospital Universitario Virgen del Rocío, Sevilla, Spain;8. Department of Medical Oncology, Biomedical Research Institute, INCLIVA, University of Valencia, Valencia, Spain;9. Hospital del Mar, Barcelona, Spain;10. Institut Català d'Oncologia and L'Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Spain;11. California Cancer Associates for Research and Excellence, San Diego, California, USA;12. Arizona Clinical Research Center, Tucson, Arizona, USA;13. Imelda General Hospital, Bonheiden, Belgium;14. County Hospital Steyr, Steyr, Austria;15. Institut de Cancerologie de l'Ouest, Saint Herblain, France;16. Calvary Mater Hospital, Newcastle, Australia;17. Aberdeen Royal Infirmary, University of Aberdeen, Aberdeen, United Kingdom;18. Roche Innovation Center Basel, Basel, Switzerland;19. Roche Innovation Center Munich, Penzberg, Germany;20. Duke University Medical Center, Durham, North Carolina, USA
Abstract:
Keywords:First-line metastatic colorectal cancer  Angiopoetin-2  VEGF-A  Vanucizumab  Bevacizumab
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