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子痫前期患者胎盘组织中Ang-1的表达及意义
引用本文:侯晓芬,张延丽. 子痫前期患者胎盘组织中Ang-1的表达及意义[J]. 中国实用医药, 2010, 5(34): 27-28
作者姓名:侯晓芬  张延丽
作者单位:1. 山西医科大学,太原,030001
2. 山西医科大学第一临床医学院妇产科
摘    要:目的探讨血管生成素-1(Ang–1)在子痫前期患者胎盘组织中的表达及意义。方法采用免疫组织化学方法检测30例正常妊娠妇女及60例子痫前期(轻度30例,重度30例)患者胎盘组织中Ang–1的表达。结果正常妊娠组、轻度、重度子痫前期组胎盘组织中Ang-1表达逐渐增强,且各组间差异具有显著性(P〈0.05)。结论子痫前期患者胎盘中Ang–1表达水平的变化可能与子痫前期的发病及病情发展有关。

关 键 词:子痫前期  Ang–1  免疫组织化学方法

Expression and significance of Ang-1 in placenta from patients with preeclampsia Patients
HOU Xiao-fen,ZHANG Yan-li. Expression and significance of Ang-1 in placenta from patients with preeclampsia Patients[J]. China Practical Medical, 2010, 5(34): 27-28
Authors:HOU Xiao-fen  ZHANG Yan-li
Affiliation:.( Gynecology and Obstetrics of first Clinical Medical College,Taiyuan 030001,China )
Abstract:Objective To study the expression and clinical significance of Ang-1 in placenta from patients with preeclampsia. Methods The expression of Ang-1 were detected in placental from 30 normal3 pregnants women and 60 patients with preeclampsia ( 30 mild preeclampsia,30 severe preeclampsia) by immunohistochemistry. Results The expressions of Ang-1 of placenta in normal pregnant,mind preeclampsia and severe preeclampsia groups were gradually increased,there were significant differences among them ( P〈0. 05). Conclusion The changes of expressional levels of Ang-1 are related to the occurrence and development of preeclampsia.
Keywords:Preeclampsia  Ang-1  Immunohistochemistry
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