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皖南地区乙型肝炎病毒基因型和亚型的分布特征
引用本文:宋骏,夏长胜. 皖南地区乙型肝炎病毒基因型和亚型的分布特征[J]. 皖南医学院学报, 2011, 30(4): 285-288. DOI: 10.3969/j.issn.1002-0217.2011.04.009
作者姓名:宋骏  夏长胜
作者单位:1. 皖南医学院附属弋矶山医院,检验科,安徽,芜湖,241001
2. 北京大学人民医院,检验科,北京,100044
摘    要:
目的:研究皖南地区人群乙型肝炎病毒(hepatitis B virus,HBV) 基因型和亚型流行及分布情况.方法:采用HBV基因型和亚型特异性引物PCR法,对皖南地区319例HBV DNA阳性患者进行基因型和亚型的检测.结果:皖南地区319例HBV感染者中,可检出基因型285例,检出率为89%,其中B型162例(57...

关 键 词:肝炎病毒  乙型  基因型  亚型  聚合酶链反应

Distribution of genotypes and subtypes of hepatitis B virus in the population of southern of Anhui Province
SONG Jun,XIA Chang-sheng. Distribution of genotypes and subtypes of hepatitis B virus in the population of southern of Anhui Province[J]. Acta Academiae Medicinae Wannan, 2011, 30(4): 285-288. DOI: 10.3969/j.issn.1002-0217.2011.04.009
Authors:SONG Jun  XIA Chang-sheng
Affiliation:SONG Jun,XIA Chang-shengDepartment of Clinical Laboratory,Yijishan Hospital,Wannan Medical College,Wuhu 241001,China
Abstract:
Objective:To investigate the distribution of genotypes and subtypes of hepatitis B virus(HBV) in the population living in southern area of Anhui Province.Methods: The genotypes were detected in 319 subjects infected with HBV by genotype/subtype-specific primer PCR.Results: HBV genotypes and subtypes were identified in 285 of the 319 serum samples(89%),and genotype B,which totally fell into sub-genotype Ba,was seen in 162(57 %) and genotype C in 49(17%) which included 38 genotypes of C1,9 of C2 and failure o...
Keywords:hepatitis B virus  genotype  sub-genotype  polymerase chain reaction(PCR)  
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