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| 黄芪预处理对缺血再灌注大鼠肾脏缝隙连接蛋白43表达的影响 | |
| 引用本文： | 唐爱国,孙浩,潘鹏,郭涛,陶美满,周留正. 黄芪预处理对缺血再灌注大鼠肾脏缝隙连接蛋白43表达的影响[J]. 江苏大学学报(医学版), 2011, 21(5): 385-389 |
| 作者姓名： | 唐爱国 孙浩 潘鹏 郭涛 陶美满 周留正 |
| 作者单位： | 江苏大学附属医院泌尿外科,江苏,镇江,212001 |
| 基金项目： | 镇江市社会发展基金资助项目 |
| 摘 要： | 目的:观察黄芪对缺血再灌注大鼠肾脏缝隙连接蛋白43(Cx43)表达的影响,探讨Cx43在抗缺血再灌注损伤中的作用及其意义.方法:30只SD大鼠平均分为假手术组、缺血再灌注(IR)组、黄芪干预组(RA组),于再灌注2 h后检测肾组织匀浆丙二醛(MDA)、超氧化物歧化酶(SOD)水平;同时进行肾组织切片,经HE染色后进行中... |
| 关 键 词： | 黄芪 缝隙连接蛋白43 缺血 再灌注损伤 |
Effect of Radix Astragali on connexin 43 expression in a rat model of renal ischemic reperfusion injury |
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| TANG Ai-guo,SUN Hao,PAN Peng,GUO Tao,TAO Mei-man,ZHOU Liu-zheng. Effect of Radix Astragali on connexin 43 expression in a rat model of renal ischemic reperfusion injury[J]. Journal of Jiangsu University Medicine Edition, 2011, 21(5): 385-389 | |
| Authors: | TANG Ai-guo SUN Hao PAN Peng GUO Tao TAO Mei-man ZHOU Liu-zheng |
| Affiliation: | TANG Ai-guo,SUN Hao,PAN Peng,GUO Tao,TAO Mei-man,ZHOU Liu-zheng(Department of Urology,the Affiliated Hospital of Jiangsu University,Zhenjiang Jiangsu 212001,China) |
| Abstract: | Objective: To observe the effect of Radix Astragali on connexin43(Cx43) expression after renal ischemic reperfusion(IR) in rats,and investigate the effect of Cx43 in the protective mechanism of Radix astragali on renal ischemic reperfusion injury.Methods: Thirty SD rats were divided into three groups randomly(n=10): Sham operated group(Sham-group),ischemic reperfusion group(IR-group),Radix Astragali group(RA-group).The rats underwent 60-minute renal ischemic and 2-hour reperfusion.The contents of MDA and SO... |
| Keywords: | Radix Astragali connexin 43 ischemic reperfusion injury |
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