Intracranial causes of death and their mechanisms |
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| Affiliation: | 1. Faculté de médecine Paris Descartes, université Sorbonne Paris Cité, université Paris Descartes, 15, rue de l’École-de-Médecine, 75006 Paris, France;2. Service de pathologie, hôpitaux universitaires Paris centre, AP–HP, site Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France;3. Service d’anatomie et de cytologie pathologiques, hôpital européen Georges-Pompidou, hôpitaux universitaires Paris Ouest, AP–HP, site HEGP, 20, rue Leblanc, 75908 Paris cedex 15, France;4. Service d’anatomie et de cytologie pathologiques, hôpital universitaire Necker–Enfants-Malades, AP–HP, 149, rue de Sèvres, 75015 Paris, France;5. Direction du numérique (DNUM), université Sorbonne Paris Cité, université Paris Descartes, 12, rue de l’École-de-Médecine, 75006 Paris, France;6. Service informatique, faculté de médecine Paris Descartes, université Sorbonne Paris Cité, université Paris Descartes, 15, rue de l’École-de-Médecine, 75006 Paris, France;7. Service d’appui aux pédagogies innovantes et à l’enseignement numérique (SAPIENS), université Sorbonne Paris Cité, rue Charles-V, 75005 Paris, France;8. Service d’anesthésie et de réanimation chirurgicale, hôpitaux universitaires Paris centre, AP–HP, site Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France;1. Department of Medicine, University of Toronto, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, and The Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada;2. Department of Laboratory Medicine & Pathobiology, University of Toronto, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, and The Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada;1. Division of Neurosurgery, Department of Biomedical and Dental Sciences, and Morpho-Functional Imaging, University of Messina, Messina, Italy;2. Division of Endocrinology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy;3. Division of Pathology, Department of Human Pathology “Gaetano Barresi”, University of Messina, Messina, Italy;4. Division of Nuclear Medicine, Department of Biomedical and Dental Sciences, and Morpho-Functional Imaging, University of Messina, Messina, Italy;1. CNRS-University of Bordeaux, Bordeaux, France;2. Loma Linda University School of Medicine, Loma Linda, CA, United States |
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| Abstract: | ![]()
Intracranial causes of death trail in incidence behind cardiovascular and respiratory system pathologies in most deaths occurring in hospitals. When intracranial pathology becomes more important is in the forensic arena, where it is often supposed that in troublesome cases such as sudden and unexpected deaths or where there appears to be no anatomic cause of death revealed in the general autopsy, the cause must be in the brain. This hope is often dashed after a careful neuropathological examination. Intracranial causes of death are discussed here mostly within the context of the forensic exercise where complex processes may be involved such as: electrophysiological dysfunctions; disorders of respiratory control; dysfunction of the intracranial pressure/volume equilibrium. |
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| Keywords: | brain death SIDS-SUID sudden death SUDEP unexpected death |
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