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Mutant TP53 disrupts age-related accumulation patterns of somatic mutations in multiple cancer types
Institution:1. Department of Computer Science, Xavier University of Louisiana, New Orleans, LA, USA;2. Tulane Cancer Center, Tulane University, New Orleans, LA, USA;1. Tumor Etiology and Screening Department of Cancer Institute and General Surgery, the First Hospital of China Medical University, Key Laboratory of Cancer Etiology and Prevention (China Medical University), Liaoning Provincial Education Department, Shenyang 110001, China;2. Hepatobiliary Surgery Department of General Surgery Institute, the First Hospital of China Medical University, Shenyang 110001, China;1. Dana Farber Cancer Institute, Boston, MA, United States;2. NRG Oncology Statistics and Data Management Center, Buffalo, NY, United States;3. University of Iowa Hospitals and Clinics, Iowa City, IA, United States;4. Stony Brook Medicine, Stony Brook, NY, United States;5. Rush University Medical Center, Chicago, IL, United States;6. Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, United States;7. Abington Memorial Hospital, Gladwyne, PA, United States;8. University of Massachusetts Memorial Health Care, Worcester, MA, United States;9. Mercer University School of Medicine, Savannah, GA, United States;10. Gynecologic Oncology of West Michigan, Grand Rapids, MI, United States;11. Massachusetts General Hospital/Dana Farber Cancer Center, Boston, MA, United States;12. The University of Chicago Medical Center, Chicago, IL, United States;2. Bioinformatics Group, Platform Development Center, CSP R&D, Samsung SDS, East Campus, Samsung SDS Tower, 123 Olympic Ro 35 Gil, Songpa-gu, Seoul 138-240, Korea;3. Department of Neurosurgery, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea;4. Cancer Research Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea;5. Department of Pathology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea
Abstract:
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