| 砂仁提取物对实验性糖尿病大鼠的降血糖作用 |
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| 引用本文： | 赵容杰,赵正林,金梅红,金相赞,梁在夏. 砂仁提取物对实验性糖尿病大鼠的降血糖作用[J]. 延边医学院学报, 2006, 29(2): 97-99 |
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| 作者姓名： | 赵容杰 赵正林 金梅红 金相赞 梁在夏 |
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| 作者单位： | [1]延边大学基础医学院药理学教研室 [2]延边大学基础医学院人体解剖学与组织胚胎学教研部,吉林延吉133000 [3]大邱韩医科大学,韩国 |
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| 摘 要： | [目的]探讨砂仁提取物对实验性糖尿病大鼠的降血糖作用.[方法]利用链脲佐菌素制作大鼠糖尿病动物模型,给糖尿病治疗组大鼠腹腔注射砂仁提取物20 mg每日2次,共2周,观察治疗前后血糖的变化及胰岛β细胞超微结构变化.[结果]糖尿病治疗组大鼠血糖明显降低,与糖尿病对照组比较有显著性差异;砂仁提取物对糖尿病大鼠胰岛β细胞具有明显的保护作用,并可改善胰岛β细胞超微结构变化.[结论]砂仁提取物对实验性糖尿病大鼠具有降血糖作用.
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| 关 键 词： | 糖尿病,实验性 植物,药用 大鼠 |
| 文章编号： | 1000-1824(2006)02-0097-03 |
| 收稿时间： | 2005-11-14 |
| 修稿时间： | 2005-11-14 |
Hypoglycemic effects of extract of Amomum Xanthoides on experimental diabetes in rats |
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| ZHAO Rong-jie,ZHAO Zheng-lin,JIN Mei-hong,KIM Sang-chan,YANG Chae-ha. Hypoglycemic effects of extract of Amomum Xanthoides on experimental diabetes in rats[J]. Journal of Medical Science Yanbian University, 2006, 29(2): 97-99 |
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| Authors: | ZHAO Rong-jie ZHAO Zheng-lin JIN Mei-hong KIM Sang-chan YANG Chae-ha |
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| Abstract: | OBJECTIVETo investigate the hypoglycemic effects of extract of Amomum Xanthoides on STZ-induced experimental diabetes in rats.METHODSThe experimental diabetic model in rats were induced by tail vein injection of STZ(30mg/kg),and those in treatment group were given 20mg of extract of Amomum Xanthoides for 2 weeks,then the blood glucose levels and the morphological changes in pancreatic islet β-cells were determined to evaluate the effects of extract of Amomum Xanthoides.RESULTSThe blood glucose level in treatment group was decreased,and there were significantly difference compared with control group;the extract of Amomum Xanthoides had protective effects on β-cells in pancreatic islets and improved morphology of β-cells in pancreatic islets in diabetic rats.CONCLUSIONThe extract of Amomum Xanthoides has hypoglycemic effects on experimental diabetes in rats. |
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| Keywords: | diabetes melhtus, experimental plants, medicinal rats |
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