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小剂量红霉素早期干预对早产儿喂养不耐受的疗效观察
引用本文:林伟豪,冯国祝,詹淑贞. 小剂量红霉素早期干预对早产儿喂养不耐受的疗效观察[J]. 海南医学院学报, 2010, 16(8): 1054-1055
作者姓名:林伟豪  冯国祝  詹淑贞
作者单位:[1]广东省深圳市坪山新区人民医院药剂科,广东深圳518118 [2]广东省深圳市坪山新区人民医院儿科,广东深圳518118
基金项目:深圳市龙岗区科技卫生立项项目
摘    要:
目的:观察小剂量红霉素早期干预对早产儿喂养不耐受的疗效。方法:将54例出现喂养不耐受的早产儿随机分为治疗组31例和对照组23例。对照组常规处理;治疗组在常规治疗基础上加用小剂量红霉素3~5mg·kg-1.d-1),静脉滴注,1次/d,疗程5~7d。结果:治疗组总有效率为83.9%,对照组总有效率为43.5%,两组比较差异有统计学意义(P<0.01)。且无明显不良反应。结论:小剂量红霉素治疗早产儿喂养不耐受安全、有效,值得临床推广应用。

关 键 词:早产儿  喂养不耐受  小剂量红霉素

Effects of small dose of erythromycin on feeding intolerance in premature infants
LIN Wei-hao,FENG Guo-zhu,ZHAN Shu-zhen. Effects of small dose of erythromycin on feeding intolerance in premature infants[J]. Journal of Hainan Medical College, 2010, 16(8): 1054-1055
Authors:LIN Wei-hao  FENG Guo-zhu  ZHAN Shu-zhen
Affiliation:1.Pharmacy Division,2.Department of Pediatrics,Pingshan New District Peaple's Hospital,Shenzhen 518118)
Abstract:
Objective:To investigate effects of small dose of erythromycin on feeding intolerance in premature infants.Methods:Fifty-four premature infants that were intolerance to feeding were randomly divided into treatment group(31 cases)and control group(23 groups).The control group was given conventional treatment,while the treatment group was also given intravenous injection of erythromycin,3-5 mg/(kg.d),once per day for 5-7 days.Results:The total effective rate of the treatment and control group was 83.9% and 43.5% separately,with significant difference between them.No obvious side reaction was observed.Conclusions:Small dose of erythromycin is safe and effective on feeding intolerance in premature infants,and is worth for application in large scale.
Keywords:Premature infants Feeding intolerance Small dose of erythromycin
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