Intestinal microvillous atrophy in a patient with Down syndrome and aganglionic megacolon |
| |
Authors: | Martínez Miguel A Egea Anastasio Serrano López Javier Manzanares Benítez Enrique Medina |
| |
Institution: |
a Department of Pathology, Hospital Universitario 12 de Octubre, Madrid, Spain.
b Department of Paediatrics, Hospital Universitario 12 de Octubre, Madrid, Spain. |
| |
Abstract: | Intestinal microvillous disorders are an uncommon cause of severe diarrhea, with very poor prognosis. The authors report the case of a female infant with Down syndrome, aganglionic megacolon, severe diarrhea, and jejunal biopsy with ultrastructural changes consistent with microvillous atrophy. The patient condition improved after a colostomy performed in the setting of the treatment of Hirschprung disease. |
| |
Keywords: | Down Syndrome Hirschprung Disease Intestinal Microvillous Atrophy |
本文献已被 InformaWorld PubMed 等数据库收录! |
|