肿瘤患者多重耐药菌医院感染分布特点及防控探讨

目的:了解广西医科大学附属肿瘤医院多重耐药菌（MDRO）分布特点，提出感染管理与预防控制措施。方法:回顾性分析2016年7月至2019年6月临床送检标本中分离出的MDRO监测资料。结果:共检出1 101株MDRO，其中产超广谱β-内酰胺酶大肠埃希菌（ESBLs-ECO）检出最多（594株，占53.95％），其次为耐甲氧西林凝固酶阴性葡萄球菌（MRCONS）（205 株，占18.62％）； 检出科室主要为妇瘤外科（168株，占15.26％），其次为重症监护病房（ICU）（157株，占14.26％）。MDRO标本来源主要以血液（303株，占27.52％）为主，其次是尿液（179株，占16.26％）。结论:该肿瘤医院MDRO感染最高为妇瘤外科；主要标本来源为血液；菌种为产超广谱β－内酰胺酶大肠埃希菌最高。应结合此特点有针对性的加强对高危科室及易感人群的防控，并制定有效的预防和控制措施，遏制MDRO的感染和传播。

Distribution characteristics and discussion on prevention and control of nosocomial infection caused by multi-drug resistant bacteria in cancer patients

Objective:To understand the distribution characteristics of multidrug resistant bacteria (MDRO) in a cancer hospital,and to put forward infection management and prevention and control measures.Methods:The monitoring data of MDRO isolated from clinical samples from July 2016 to June 2019 were retrospectively analyzed.Results:A total of 1 101 MDRO strains were detected,of which 594 strains (53.95%) were escherichia coli producing extended-spectrum beta-lactamases (ESBLs-ECO),followed by methicillin-resistant coagulase-negative staphylococcus (MRCONS) (205 strains,18.62%).The detection department was mainly gynecological surgery (168 strains,accounting for 15.26%),followed by intensive care unit (ICU) (157 strains,accounting for 14.26%).The main source of MDRO specimens was blood (303 strains,27.52%) and urine (179 strains,16.26%).Conclusion :The highest MDRO infection in this tumor hospital is gynecologic surgery.The main source of specimens is blood.And escherichia coli producing extended-spectrum beta-lactamases is the highest strain.Combining this characteristic,we should strengthen the prevention and control of high-risk departments and susceptible groups,and formulate effective prevention and control measures to curb the infection and spread of MDRO.