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局部外用β受体阻滞剂治疗婴幼儿血管瘤的临床应用研究进展
引用本文:顾达,霍然,徐广琪,毕见海,李尚滨.局部外用β受体阻滞剂治疗婴幼儿血管瘤的临床应用研究进展[J].中国口腔颌面外科杂志,2020,18(4):375-380.
作者姓名:顾达  霍然  徐广琪  毕见海  李尚滨
作者单位:1.山东第一医科大学附属济南市中心医院 整形外科,山东 济南 250000;
2.山东第一医科大学附属省立医院 烧伤整形外科,山东 济南 250000
摘    要:血管瘤是婴幼儿最常见的良性肿瘤。根据部位、大小、范围、深度、分期、对患儿功能和心理的影响等因素不同,以局部外用和系统用药为主,辅以激光或局部药物注射。目前口服普萘洛尔是治疗浅表性血管瘤的一线药物,然而局部外用β受体阻滞剂更易于被患儿家长接受,其使用人数逐步增多。本文就近年来报道的有关β受体阻滞剂治疗婴幼儿血管瘤的研究现状进行综述,为婴幼儿血管瘤的临床治疗提供理论依据。

关 键 词:婴幼儿血管瘤  浅表型  普萘洛尔  噻吗洛尔  局部外用  
收稿时间:2019-03-06

Progress in topical of application β-blockers in the treatment of infantile hemangioma
GU Da,HUO Ran,XU Guang-qi,BI Jian-hai,LI Shang-bin.Progress in topical of application β-blockers in the treatment of infantile hemangioma[J].China Journal of Oral and Maxillofacial Surgery,2020,18(4):375-380.
Authors:GU Da  HUO Ran  XU Guang-qi  BI Jian-hai  LI Shang-bin
Institution:1. Department of Plastic Surgery, Jinan Central Hospital Affiliated to Shandong First Medical University. Jinan 250000, Shandong Province;
2. Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University. Jinan 250000, Shandong Province, China
Abstract:Hemangioma is the most common benign tumor in infants and young children. It is mainly treated by topical and systemic medication, supplemented by laser therapy, depending on the location, size, extent, depth, stage, functional and psychological impact on children. Oral propranolol is currently the first-line treatment for superficial hemangioma. However, topical β-blockers are more likely to be accepted by children's parents, and their use is gradually increasing. This article reviewed the research progress of β-blockers in the treatment of infantile hemangiomas in recent years, with the aim to provide a theoretical basis for the treatment of infantile hemangiomas.
Keywords:Infantile hemangioma  Superficial  Propranolol  Timolol  Topical application  
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