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| 流体剪应力对血管内皮细胞的作用研究与应用 | |
| 引用本文： | 胡江 陈槐卿. 流体剪应力对血管内皮细胞的作用研究与应用[J]. 生物医学工程与临床, 2000, 4(2): 63-66 |
| 作者姓名： | 胡江 陈槐卿 |
| 作者单位： | [1]中国科学院力学研究所微重力室,北京100080 [2]华西医科大学生物医学工程研究室 |
| 摘 要： | 血管内皮层具有重要的生理功能。血流剪应力作用影响内皮细胞的形态结构、功能、增殖和迁移过程。其作用是通过应力转导途径实现的。对应力转导的深入研究，不仅揭示了人体血管内的许多生理过程，解释动脉粥样硬化等心血管疾病的病理机理，而且可将其机理应用于改进临床治疗手段。 |
| 关 键 词： | 流体剪应力 血管内皮细胞 应力转导 内皮化 |
The Effect of Fluid Shear Stress on Vascular Endothelial Cells: Mechanism and Applications |
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| Hu Jiang Institute of Mechanics,Chinese Academy of Science,Beijing. The Effect of Fluid Shear Stress on Vascular Endothelial Cells: Mechanism and Applications[J]. Biomedical Engineering and Clinical Medicine, 2000, 4(2): 63-66 | |
| Authors: | Hu Jiang Institute of Mechanics Chinese Academy of Science Beijing |
| Affiliation: | Hu Jiang Institute of Mechanics,Chinese Academy of Science,Beijing 100080 |
| Abstract: | Vascular endothelium plays an important role in maintaining vascular morphology and biologic functions. Fluid shear stress influences the morphology, function, proliferation and migration of endothelial cells via mechanotransduction pathway. Knowledge on mechanism of mechanotransduction not only allows defining the physiological and pathological process in vascular system, but also has clinical applications for the development of new and effective treatments. |
| Keywords: | Shear stress Endothelial cells Mechanotransduction Endothelialization |
| 本文献已被 CNKI 维普 等数据库收录！ | |