| 氯丙嗪、氯氮平和利培酮对血糖的影响 |
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| 引用本文： | 林文嫦. 氯丙嗪、氯氮平和利培酮对血糖的影响[J]. 海南医学院学报, 2007, 13(1): 45-46,49 |
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| 作者姓名： | 林文嫦 |
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| 作者单位： | 海南省安宁医院,海南海口,571100 |
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| 摘 要： | 目的:比较氯丙嗪、氯氮平和利培酮对精神分裂症血糖的影响.方法:对88例首发精神分裂症患者随机分为3组,单用氮丙嗪、氯氮平和利培酮治疗,疗程8周.分别在治疗前及治疗后4、8周末采用Rayto-200c全自动生化分析仪对患者血糖进行对比分析.结果:氯氮平组的精神分裂症患者治疗后血糖较治疗前明显升高(P＜0.01),氯丙嗪和利培酮组治疗后血糖无明显变化(P＞0.05).结论:氯氮平可引起精神分裂症患者糖代谢的异常,在使用氯氮平对患者进行治疗时应注意监测血糖.
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| 关 键 词： | 精神分裂症 血糖 氯丙唾 氯氮平 剁培酮 |
| 文章编号： | 1007-1237（2007）01-0045-02 |
| 修稿时间： | 2006-08-31 |
Effects of antipsychotic chlorderazin,clozapine and risperidone on blood glucose |
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| LING Wen-chang. Effects of antipsychotic chlorderazin,clozapine and risperidone on blood glucose[J]. Journal of Hainan Medical College, 2007, 13(1): 45-46,49 |
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| Authors: | LING Wen-chang |
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| Affiliation: | Anning Hospital of Hainan province, Hainan Haikou 571100, P.R. China |
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| Abstract: | Objective:To understand the effects of antipsychotic,chlorderazin,clozapine and risperidone on blood glucose in patients with schizophrenia.Methods: Eighty eight patients first onset with schizophrenia were randomly divided into three groups,each group treated with chlorderazin,clozapine and Risperidone respectively for 8 weeks.The blood glucose,using Rayto-200c automatic biochemistry analyzer,was tested before treatment, at 4 and 8 weeks management.Results:The blood glucose level was higher in group clozapine than other two groups(P<0.01),but no changes in group chlorderazin and Risperidone before and after drug treatment(P>0.05).Conclusion: Clozapine can produce metabolic disorder of blood glucose.We should monitor it when initiate clozapine for patients. |
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| Keywords: | Schizophrenia Blood glucose Chlorderazin Clozapine Risperidone |
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