早产的预测

早产是围生儿患病和围生儿死亡的最主要因素,因此预测早产具有重要的临床意义.早产往往是一些隐藏的病理情况的具体表现,这些病理情况会导致子宫,特别是子宫颈的生理和生化性的改变.宫颈的生理变化主要表现为宫颈的缩短和宫颈口的扩张,生化改变则比较复杂,有许多生化因子被证实和早产有关,该文就近几年研究比较多、具有一定临床指导意义的一些早产预测指标研究进展作以综述.

Prediction of preterm delivery

Preterm delivery,which occurs before 37 weeks of gestation,is a leading cause of perinatal morbidity and mortality.So it becomes very important to predict an impending preterm delivery.Preterm delivery is usually the result of many latent pathologic conditions.Some pathologic conditions can cause some physiological and biochemical changes in uterus,especially cervix.The physiological changes of the cervix mainly manifest shortening of the cervix or expansion of the cervical orifice.Biochemical changes are very complicated and many biochemical factors are confirmed to have some association with preterm delivery.This article reviewed the latest progress in research on prediction index of this disease so as to provide some advices for obstetricians.