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Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity
Authors:Chaudhuri Rekha  McSharry Charles  Brady Jeffrey  Donnelly Iona  Grierson Christal  McGuinness Stephen  Jolly Lisa  Weir Christopher J  Messow C Martina  Spears Mark  Miele Gino  Nocka Karl  Crowther Dan  Thompson Joyce  Brannigan Maureen  Lafferty Jane  Sproule Michael  Macnee William  Connell Martin  Murchison John T  Shepherd Malcolm C  Feuerstein Giora  Miller Douglas K  Thomson Neil C
Affiliation:a Respiratory Medicine, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom
b Immunology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom
c Pfizer Research/Translational Medicine Research Collaboration, Dundee, United Kingdom, Cambridge, Mass, and Collegeville, Pa
d MRC Hub for Trials Methodology Research, University of Edinburgh, Edinburgh, United Kingdom
e Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom
f Radiology Department, Gartnavel General Hospital, Glasgow, United Kingdom
g MRC Centre for Inflammation Research, Medical Physics and Clinical Radiology, University of Edinburgh, Edinburgh, United Kingdom
Abstract:
Keywords:Matrix metalloproteinase 12   tissue inhibitor of metalloproteinases 1 and 2   MMP12 expression   emphysema   chronic obstructive pulmonary disease   asthma   smoker
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