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TC/GLU和LDL-C/HDL-C比值与结直肠息肉的相关性研究
引用本文:徐铭卿,缪姝妹,孙鲁宁,李文洁,马梦圆,王永庆. TC/GLU和LDL-C/HDL-C比值与结直肠息肉的相关性研究[J]. 药学与临床研究, 2021, 29(3): 161-164
作者姓名:徐铭卿  缪姝妹  孙鲁宁  李文洁  马梦圆  王永庆
作者单位:徐州医科大学 江苏省新药研究与临床药学重点实验室,徐州 221004;江苏省人民医院 药学部,南京 210029;江苏省人民医院 信息处,南京 210029;江苏省人民医院 药学部,南京 210029;南京医科大学 药学院,南京 210029;江苏省人民医院 消化内科,南京 210029;徐州医科大学 江苏省新药研究与临床药学重点实验室,徐州 221004;江苏省人民医院 药学部,南京 210029;南京医科大学 药学院,南京 210029
基金项目:国家自然科学基金面上项目(81870436)
摘    要:
目的:研究总胆固醇与空腹血糖比值(TC/GLU)和低密度脂蛋白胆固醇与高密度脂蛋白胆固醇比值(LDL-C/HDL-C)对结直肠息肉的预测价值.方法:选取2017年2月至2018年12月在江苏省人民医院经肠镜检查的消化内科患者共2150例,收集患者肠镜前空腹静脉血中的TC、HDL-C、LDL-C、甘油三酯(TG)、GLU...

关 键 词:结直肠息肉  总胆固醇  低密度脂蛋白胆固醇  高密度脂蛋白胆固醇  血糖
收稿时间:2021-01-30
修稿时间:2021-06-10

Study on TC/GLU and LDL-C/HDL-C Related to the Incidence of Colorectal Polyp
Xu Mingqing,Miao Zhumei,Sun Luning,Li Wenjie,Ma Mengyuan and Wang Yong-qinga. Study on TC/GLU and LDL-C/HDL-C Related to the Incidence of Colorectal Polyp[J]. Pharmacertical and Clinical Research, 2021, 29(3): 161-164
Authors:Xu Mingqing  Miao Zhumei  Sun Luning  Li Wenjie  Ma Mengyuan  Wang Yong-qinga
Abstract:
Objective: To study the predictive value of the ratio of total cholesterol to blood glucose (TC/GLU) and the ratio of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C) for colorectal polyp (CP). Methods: A total of 2150 patients underwent colonoscopy in the Department of Gastroenterology, Jiangsu People''s Hospital from February 2017 to December 2018. The colonoscopy results, the collected data of blood TC, triglycerides (TG), HDL-C, LDL-C and GLU, and the ratio of TC/GLU and LDL-C/HDL-C were statistically analyzed. Results: According to the results of univariate analysis and multivariate logistic regression analysis, LDL-C/HDL-C and TC/GLU were independent influencing factors for CP. The results of the receiver operating characteristic (ROC) curve showed that the effect of the combined factors with LDL-C/HDL-C and TC/GLU on CP was significantly better than the independent factors. Conclusion: Multivariate diagnosis of TC/GLU and LDL-C/HDL-C ratios has a better predictive value for the incidence of CP.
Keywords:Colorectal polyp   Total cholesterol   Low-density lipoprotein cholesterol   High-density lipoprotein cholesterol   Blood glucose
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