| 心房利钠肽与心血管疾病 |
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| 引用本文： | 穆成,郭刚,张镜宇. 心房利钠肽与心血管疾病[J]. 国际内分泌代谢杂志, 2006, 26(Z1): 21-23 |
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| 作者姓名： | 穆成 郭刚 张镜宇 |
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| 作者单位： | 300070,天津医科大学内分泌研究所 |
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| 摘 要： | 心房利钠肽属于利钠肽家族,其通过与受体结合激活鸟苷酸环化酶,促进细胞内环鸟苷酸水平升高而发挥生物学功能。心房利钠肽具有利钠、利尿、舒张血管平滑肌、抑制细胞增殖等多种作用,在维持血压,水、钠平衡以及在心血管疾病的病理生理过程中发挥重要作用。
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| 关 键 词： | 心房利钠肽 信号转导 心血管疾病 |
| 修稿时间： | 2005-09-13 |
Atrial natriuretic peptide and cardiovascular diseases |
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| MU Cheng,GUO Gang,ZHANG Jing-yu. Atrial natriuretic peptide and cardiovascular diseases[J]. International JOurnal of Endocrinology and Metabolism, 2006, 26(Z1): 21-23 |
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| Authors: | MU Cheng GUO Gang ZHANG Jing-yu |
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| Abstract: | Atrial natriuretic peptide(ANP) is a member of the natriuretic peptide family. By binding with its receptor and thereafter activating guanylate cyclase, ANP increases intracellular cGMP level and hence produces biological effects. ANP exerts diuretic, natriuretic, vasorelaxant and antiproliferative actions and plays an important role in main-tening blood pressure, balance of fluid and sodium and also in the pathophysiology of cardiovascular diseases. |
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| Keywords: | Atrial natriuretic peptide Signal transduction Cardiovascular diseases |
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