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| 单核细胞趋化蛋白1与细胞凋亡 | |
| 引用本文： | 徐学超,吴艳. 单核细胞趋化蛋白1与细胞凋亡[J]. 医学综述, 2011, 17(21): 3225-3228 |
| 作者姓名： | 徐学超 吴艳 |
| 作者单位： | 华中科技大学同济医学院附属协和医院皮肤科,武汉,430022 |
| 摘 要： | 单核细胞趋化蛋白1(MCP-1)是一种分泌型单链蛋白质,为趋化因子家族成员之一,可通过G蛋白耦联受体途径诱导趋化性的产生,是调节单核巨噬细胞迁移及浸润的主要趋化因子之一。MCP-1参与多种疾病的细胞凋亡过程,并在凋亡机制中发挥重大作用。现就其特点、功能及与细胞凋亡性疾病的关系予以综述。 |
| 关 键 词： | 单核细胞趋化蛋白1 细胞凋亡 单核细胞趋化蛋白1诱导蛋白 |
Monocyte Chemoattractant Protein-1 and Apoptosis |
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| XU Xue-chao,WU Yan. Monocyte Chemoattractant Protein-1 and Apoptosis[J]. Medical Recapitulate, 2011, 17(21): 3225-3228 | |
| Authors: | XU Xue-chao WU Yan |
| Affiliation: | XU Xue-chao,WU Yan,FENG Ai-ping.(Department of Dermatology,Union Hospitol,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China) |
| Abstract: | Monocyte chemoattractant protein-1(MCP-1)is a secretory single stranded protein,which is a member of C-C chemokine family and induces chemotaxis through the activation of G-protein-coupled receptors.Also MCP-1 is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages.Recent studies have shown that MCP-1 participate in cell apoptosis process in various diseases and play a great role in apoptosis mechanisms.Here is to review its features,functions and the it correlation wi... |
| Keywords: | Monocyte chemoattractant protein-1 Apoptosis Monocyte chemoattractant protein-1-induced protein |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |