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| 内皮祖细胞在急慢性肺损伤治疗中的研究进展 | |
| 引用本文： | 任建立. 内皮祖细胞在急慢性肺损伤治疗中的研究进展[J]. 医学综述, 2011, 17(17) |
| 作者姓名： | 任建立 |
| 作者单位： | 北京军区总医院心肺血管中心一区,北京,100700 |
| 摘 要： | 内皮祖细胞(EPCs)是一种特殊表型的造血干细胞,它可以分化为成熟内皮细胞。近年来研究表明,EPCs肺组织损伤修复过程中有着重要作用。除了具有保护肺泡毛细血管屏障完整,减轻炎性反应,减轻肺组织损伤的作用外,EPCs还具有替代紊乱的肺血管内皮,防止肺血管重构,降低肺动脉压力的能力。目前EPCs移植在治疗急性肺损伤、慢性肺动脉高压方面的研究也取得了一定进展。 |
| 关 键 词： | 内皮祖细胞 肺损伤 治疗 |
Recent Studies of Endothelial Progenitor Cells in the Treatment of Acuteand Chronic Lung Injury |
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| REN Jian-li. Recent Studies of Endothelial Progenitor Cells in the Treatment of Acuteand Chronic Lung Injury[J]. Medical Recapitulate, 2011, 17(17) | |
| Authors: | REN Jian-li |
| Affiliation: | REN Jian-li1,YAO Jian-min1,REN Hua2.(1.Department 1 of Cardiopulmonary Center,the Military General Hospital of Beijing,Beijing 100700,China,2.Department of Pediatrics,Yanan University Affiliated Hospital,Yanan 716000,China) |
| Abstract: | Endothelial progenitor cells(EPCs) are a specficc subtype of hematopoietic stem cells that have the propensity to differentiate into mature endothelial cells.Resent studies showed circulating endothelial progenitor cells played an important role in lung wound healing.Besides restoring pulmonary endothelialfunction,preserving integrity of the alveolocapillary barrier and suppressing the lung inflammatory response,EPCs can reverse endothelial dysfunction,inhibited pulmonary vessel remodeling,reduced pulmonary... |
| Keywords: | Endothelial progenitor cells Lung injury Treatment |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |