| SD大鼠肺中降钙素基因相关肽的分布及缺氧对其含量的影响 |
| |
| 引用本文： | 杨炯,段生福,刘绍春.SD大鼠肺中降钙素基因相关肽的分布及缺氧对其含量的影响[J].华中科技大学学报(医学版),1992(5). |
| |
| 作者姓名： | 杨炯 段生福 刘绍春 |
| |
| 作者单位： | 同济医科大学附属同济医院呼吸病研究室
(杨炯，段生福)，同济医科大学基础医学部病理学教研室(刘绍春) |
| |
| 摘 要： | 本研究用免疫细胞化学方法(ABC法)观察了降钙素基因相关肽(CGRP)在SD大鼠肺中的分布,缺氧对肺中神经内分泌细胞内CGRP含餐的影响。结果表明:含CGRP的神经纤维分布在肺血管平滑肌层中及其周围、气管-支气管树的粘膜下层;含CGRP的神经内分泌细胞位于气管一支气管树的上皮层、粘液腺中和肺实质内。缺氧不引起火鼠肺的神经内分泌细胞数目改变,但可使这些细胞内的CGRP含量增加。
|
| 关 键 词： | 降钙素基因相关肽 肺 神经内分泌细胞 缺氧 |
Distribution of Calcitonin Gene-related Peptide in the Rat Lung and Effect of Hypoxia on Its Quantity |
| |
| Yang Jiong,Duan ShengfuResearch Unit of Respiratory Diseases,Tongji Hospital,Tongji Medical University,WuhanLiu Shaochun.Distribution of Calcitonin Gene-related Peptide in the Rat Lung and Effect of Hypoxia on Its Quantity[J].Journal of Huazhong University of Science and Technology(Health Sciences),1992(5). |
| |
| Authors: | Yang Jiong Duan ShengfuResearch Unit of Respiratory Diseases Tongji Hospital Tongji Medical University WuhanLiu Shaochun |
| |
| Institution: | Yang Jiong,Duan ShengfuResearch Unit of Respiratory Diseases,Tongji Hospital,Tongji Medical University,WuhanLiu ShaochunDepartment of Pathology,Faculty of Basic Medical Sciences,Tongji Medical University,Wuhan |
| |
| Abstract: | We observed the distribution of calcitonin gene-related peptide in the SD rat lung and the effect of hypoxia on its quantity by means of immuno-cytochemistry (ABC method). The results show that the CGRP-containing nerve fibers were distributed among smooth muscle, around blood vessels; beneath the epithelium of the trachea-bronchial trees. CGRP-containing endocrine cells were localized within the epithelium of trachea-bronchial trees, in the seromucous glands, and in the lung parenchyma. Hypoxia did not change the number of endocrine cells, but increased the intracellular levels of CGRP. |
| |
| Keywords: | calcitonin gene-related peptide lung neurocndocrine cell hypoxia |
| 本文献已被 CNKI 等数据库收录！ |
