补肺正气汤与穴位贴敷联合常规疗法治疗肺气亏虚型肺心病临床研究

目的 评价补肺正气汤与穴位贴敷联合常规疗法治疗肺气亏虚型肺心病的疗效.方法 将符合入选标准的100例肺气亏虚型肺心病患者采用随机数字表法分为2组,每组50例.对照组采用常规疗法治疗,研究组在对照组基础上结合补肺正气汤与穴位贴敷治疗.2组均治疗8周.采用肺功能测试仪检测第1秒用力呼气容积(forced expiratory volume in one second,FEV1)、峰值呼气流速(peak expiratory flow,PEF)、用力呼气量占用力肺活量比值(forced expiratory volume in one second/forced vital capacity,FEV1/FVC);采用免疫透射比浊法检测免疫球蛋白A(immunoglobulin A,IgA)、免疫球蛋白G(immunoglobulin G,IgG)、补体C3(serum C3,C3)表达水平,评价临床疗效.结果 研究组总有效率为96.0%(48/50)、对照组为84.0%(42/50),2组比较差异有统计学意义(U=8.130,P=0.043).治疗后,研究组FEV1[(65.26±5.34)%比(61.52±6.21)%,t=3.229]、FEV1/FVC[(67.59±5.86)%比(64.68±5.52)%,t=2.556]水平均高于对照组(P<0.05);研究组IgA[(2.37±0.53)g/L比(1.83±0.76)g/L,t=4.121]水平高于对照组(P<0.01).结论 补肺正气汤与穴位贴敷联合常规疗法可有效改善肺气亏虚型肺心病患者的肺功能和免疫功能状况,疗效优于常规疗法治疗.

Clinical study on treatment of pulmonary heart disease with pulmonary Qi deficiency syndrome by theBufei-Zhengqi decoction and acupoint application combined with western medicine

Objective To explore the effect of Babu patch combined with Bufei-Zhengqi decoction on lung function and immunological indexes of pulmonary heart disease with Fei qi deficiency.Methods A total of 100 patients with pulmonary heart disease were randomly divided into study group and control group, 50 in each group. The control group was treated with routine therapy, the study group was treated with routine therapy and integrated Chinese medicine therapy (Babu patch combined with Bufei-Zhengqi decoction). Both groups were treated for 8 weeks. The effect of the two groups, and the lung function index, immunological indexes and adverse reaction were evaluated.Results The total effective rate in study group was 96.0% (48/50), the total effective rate in control group 84.0% (42/50), and there was significantly higher than that of the control group (χ2=8.130, P=0.043). After treatment, the lung function indexes FEV1 (65.26% ± 5.34%vs. 61.52% ± 6.21%,t=3.229), FEV1/FVC (67.59% ± 5.86%vs. 64.68% ± 5.52%,t=2.556) of study group were significantly higher than those of the control group (P<0.05). The IgA (2.37 ± 0.53 g/Lvs. 1.83 ± 0.76 g/L,t=4.121) in study group were significantly higher than the control group (P<0.01).Conclusions The application of Babu patch combined withBufei-Zhengqi decoction therapy, meet the requirements of treatment, improve lung function and immune function.