|
|||||
|
|
Toll-Like Receptor 2 Arg677Trp Polymorphism Is Associated with Susceptibility to Tuberculosis in Tunisian Patients |
|
| Authors: | Meriem Ben-Ali Mohamed-Ridha Barbouche Soufia Bousnina Abdellatif Chabbou Koussay Dellagi |
| Abstract: | Toll-like receptor 2 (TLR2) is critical in the immune response to mycobacteria. Herein, we report that the frequency of a human TLR2 Arg677Trp polymorphism (C2029T nucleotide substitution) in tuberculosis patients in Tunisia is significantly higher than in healthy controls (P < 0.0001). This finding suggests that this polymorphism could be a risk factor for tuberculosis. |
| Keywords: | |