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Importance of early nutritional screening in patients with gastric cancer
Authors:Gavazzi Cecilia  Colatruglio Silvia  Sironi Alessandro  Mazzaferro Vincenzo  Miceli Rosalba
Affiliation:Clinical Nutrition Unit, National Cancer Institute, Via Venezian 1, 20133 Milan, Italy. cecilia.gavazzi@istitutotumori.mi.it
Abstract:In the present study, we evaluated the relationship between nutritional status, disease stage and quality of life (QoL) in 100 patients recently diagnosed with gastric carcinoma. The patients' nutritional status was investigated with anthropometric, biochemical, inflammatory and functional variables; and we also evaluated the nutritional risk with the Nutritional Risk Screening 2002. Oncological staging was standard. QoL was evaluated using the Functional Assessment of Anorexia/Cachexia Therapy questionnaire. The statistical correlation between nutritional risk score (NRS) and oncological characteristics or QoL was evaluated using both univariable and multivariable analyses. Weight loss and reduction of food intake were the most frequent pathological nutritional indicators, while biochemical, inflammatory and functional variables were in the normal range. According to NRS, thirty-six patients were malnourished or at risk for malnutrition. Patients with NRS?≥?3 presented a significantly greater percentage of stage IV gastric cancer and pathological values of C-reactive protein, while no correlation was found with the site of tumour. NRS was negatively associated with QoL (P?
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