| 原发性高血压微白蛋白尿与眼底病变的关系 |
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| 引用本文： | 王红纲,华卫红,吕少彬,谭华,闫志兴. 原发性高血压微白蛋白尿与眼底病变的关系[J]. 青岛大学医学院学报, 1995, 0(4) |
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| 作者姓名： | 王红纲 华卫红 吕少彬 谭华 闫志兴 |
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| 作者单位： | 青岛市第二人民医院，山东省淄博市临淄区人民医院 |
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| 摘 要： | 对７２例肾功能正常的原发性高血压病人的尿白蛋白排泄率（ＵＡＥＲ）进行了检测。结果表明，３４例呈微白蛋白尿（ＭＡＵ），３８例ＵＡＥＲ正常。经１周有效抗高血压治疗后，ＭＡＵ组的ＵＡＥＲ显著下降（Ｐ＜０．０１），其中２３例ＵＡＥＲ仍增高（持续性ＭＡＵ），１１例ＵＡＥＲ降为正常（可逆性ＭＡＵ）。持续性ＭＡＵ组中，高血压眼底病变的发生率为８６％，显著高于可逆性ＭＡＵ组（２７％）（Ｐ＜０．０１）及ＵＡＥＲ正常组（２９％）（Ｐ＜０．０１）。提示有效的降血压治疗可降低原发性高血压病人的ＵＡＥＲ，持续性ＭＡＵ是原发性高血压病人发生微血管病变的标志。
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| 关 键 词： | 高血压；白蛋白尿；眼底病变 |
CORRELATION BETWEEN MICROALBUMINURIS AND RETINOPATHY IN ESSENTIAL HYPERTENSIVE PATIENTS |
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| Wang Honggang, Hua Weihong, Lu Shaobin,et al. CORRELATION BETWEEN MICROALBUMINURIS AND RETINOPATHY IN ESSENTIAL HYPERTENSIVE PATIENTS[J]. Acta Academiae Medicinae Qingdao Universitatis, 1995, 0(4) |
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| Authors: | Wang Honggang Hua Weihong Lu Shaobin et al |
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| Affiliation: | Department of Nephrology |
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| Abstract: | In 72 insufficiently treated essential hypertensive patients with normal renal function,the mean urinary albumin excretion rate(UAER) was tested.34 patients showed microalbuminuria, while in the remaining 38 the UAER was normal.After a week of effective antihypertensive treatment,the UAER in the microalbuminuria group decreased significantly(P<0.01).23 patients in this group showed persistent microalbuminuria while in the other 11 patients with primary microalbuminuria the UAER became normal.In the patients with persistent microalbuminuria,the prevalence of hypertensive retinopathy was 86% in comparison with the 27% in patients with reversible microalbuminuria(P<0.01).The results indicate that the presence of persistent microalbuminuria can be regarded as an indicator of general microvascular damage in essential hyper tension. |
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| Keywords: | hypertension albuminuria retinopathy |
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