HELLP综合征临床多学科综合治疗分析

目的 探讨HELLP综合征多学科综合治疗的治疗方法和临床结局。方法 选择2011年1月至2015年12月安徽医科大学第一附属医院收治的26例HELLP综合征患者患者，回顾分析患者的临床资料和治疗情况。结果 26例HELLP综合征中，完全性HELLP 7例，部分性HELLP 19例；24例重度子痫前期，2例子痫；25例进行了急诊剖宫产手术。患者发生可逆性后部脑病综合征1例、急性肾损伤3例、急性呼吸窘迫综合征4例、胎盘早剥并发失血性休克2例、多脏器功能障碍综合征1例。2例患者进行了血液净化治疗，4例患者进行了机械通气治疗。25例救治成功，1例死亡。结论 HELLP综合征是妊娠期高血压疾病的严重并发症，及时终止妊娠是治疗的关键，机械通气和血液净化是重要的治疗手段。

Analysis of clinical multidisciplinary treatment of HELLP syndrome

Objective To explore the treatment methods and clinical outcomesof multidisciplinary comprehensive treatment for HELLP syndrome. Methods The clinical data and treatment of 26 patients with HELLP syndrome admitted to the intensive care unit from January 2011 to December 2015 were analyzed retrospectively.Results There were 7 cases with complete HELLP syndrome and 19 cases with partial HELLP syndrome. 24 cases with severe preeclampsia,2 cases with epilepsy,all were combined with varying degrees of hypertension.Emergency cesarean section was performed in 25 cases. The maternal complications included posterior reversible encephalopathy syndrome(1 case),acute renal injury(3 cases),acute respiratory distress syndrome(4 cases),placental abruption and hemorrhagic shock(2 cases),multiple organ dysfunction syndrome(1cases).Two patients were treated with hemodialysis,four patients underwent mechanical ventilation. 25 cases were cured,1 cases died.Conclusion HELLP syndrome is a serious complication of pregnancy-induced hypertension,timely termination of pregnancy is the key to improve the cure rate,mechanical ventilation and hemodialysis are important treatment methods.