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Increased apoptosis and secretion of tryptase by mast cells in infantile haemangioma treated with propranolol
Affiliation:1. PathWest, Queen Elizabeth II Medical Centre, Nedlands, and University of Western Australia, WA, Australia;2. Envoi Pathology, Herston, Qld, Australia;3. Sir Charles Gairdner Hospital, Nedlands, WA, Australia;4. Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, and Westmead Clinical School, University of Sydney, Sydney, NSW, Australia;5. Department of Histopathology, The Children’s Hospital at Westmead, Sydney, NSW, Australia;6. Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, NSW, Australia;7. St John of God Hospital Murdoch, Murdoch, and Department of Surgery, Fremantle Hospital, Fremantle, WA, Australia;8. Cancer Diagnosis and Pathology Group, University of Sydney, NSW, Australia;9. Griffith Medical School and Griffith Health Institute, Griffith University, Qld, Australia;10. Department of Medical Oncology, The Queen Elizabeth Hospital and University of Adelaide, Adelaide, SA, Australia;11. St. Michael’s Hospital, Toronto, Canada;12. Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States;1. Department of Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia;2. University Malaya Cancer Research Institute (UMCRI), Kuala Lumpur, Malaysia;3. Centre for Kidney Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, Brisbane, Qld, Australia;4. Department of Pathology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia;5. University Malaya Medical Centre, Kuala Lumpur, Malaysia;1. Department of Laboratory Animal Science, School of Medicine, Shanghai Jiao Tong University, Shanghai, P. R. China;2. Monell Chemical Senses Center, Philadelphia, PA, United States
Abstract:
Keywords:Apoptosis  endothelial cells  immunohistochemistry  infantile haemangioma  mast cells  mesenchymal stem cell  microvessel maturity  osteoprotegerin (OPG)  propranolol  tryptase
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