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Current management of acute malignant large bowel obstruction: a systematic review
Affiliation:1. Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL, C/ Feixa Llarga s/n, L''Hospitalet de Llobregat, 08907 Barcelona, Spain;2. Department of Surgery, Colorectal Unit, Gregorio Marañon General University Hospital, Madrid, Spain;1. Department of Gastrointestinal Surgery, Guizhou Provincial People''s Hospital, Guiyang, China;2. Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China;3. Department of Stomatology, Guizhou Provincial People''s Hospital, Guiyang, China;1. Department of Colorectal Surgery, Royal Prince Alfred Hospital, NSW, Australia;2. Surgical Outcomes Research Centre (SOuRCe), University of Sydney, Sydney, Australia;3. University of Sydney, Sydney, Australia;1. Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan;2. Department of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan;3. Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan;4. Department of Gastroenterology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Japan;5. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Ohashi Medical Center, Tokyo, Japan;6. Department of Surgery, Moriguchi Keijinkai Hospital, Osaka, Japan;7. Department of Gastroenterology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan;8. Department of Surgery, National Hospital Organization Yokohama Medical Center, Yokohama, Japan;9. Department of Surgery, Kishiwada Tokushukai Hospital, Osaka, Japan;10. Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan;11. Department of Gastroenterology, Kameda Medical Center, Kamogawa, Japan;12. Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;13. Department of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan
Abstract:BackgroundThe management of colonic obstruction has changed in recent years. In distal obstruction, optimal treatment remains controversial, particularly after the appearance and use of colonic endoluminal stents. The purpose of this study was to review the current treatment of acute malignant large bowel obstruction according to the level of evidence of the available literature.MethodsA systematic search was conducted in PubMed, MEDLINE, Embase, and Google Scholar for articles published through January 2013 to identify studies of large bowel obstruction and colorectal cancer. Included studies were randomized and nonrandomized controlled trials, reviews, systematic reviews, and meta-analysis.ResultsAfter a literature search of 1,768 titles and abstracts, 218 were selected for full-text assessment; 59 studies were ultimately included. Twenty-five studies of the diagnosis and treatment of obstruction and 34 studies of the use of stents were assessed.ConclusionsIn view of the various alternatives and the lack of high-grade evidence, the treatment of distal colonic obstruction should be individually tailored to each patient.
Keywords:Malignant large bowel obstruction  Systematic review  Surgical treatment  Colonic stent
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