泌尿生殖道支原体、衣原体感染检测及药敏分析

目的探讨本地区泌尿生殖道感染患者支原体、衣原体感染情况,分析其对抗生素的敏感性。方法衣原体抗原检测采用单克隆抗体胶体金法;支原体检测及其药物敏感试验采用培养法。结果支原体药敏试验结果显示,Uu对四环素、氧氟沙星、司帕沙星、左氧氟沙星的耐药率分别为27.1%、40.4%、32.0%、34.0%,Uu＋Mh对上述药物的耐药率分别为40.0%、60.0%、50.0%、50.0%;多西环素、交沙霉素、米诺环素、克拉霉素有较高的抑菌能力。结论支原体的耐药性在不同地区表现不同,临床应参照药敏试验结果选用抗菌表治疗患者,多西环素、交沙霉素、米诺环素和克拉霉素可作为本地区临床治疗支原体感染患者的首选药。

Prevalence and antibiotic susceptibility of genital mycoplasma and Chlamydia trachomatis

Objective To investigate the prevalence and antibiotic susceptibility of genital Chlamydia trachomatis and mycoplasma infection in the local area.Methods To detect Chlamydia trachomatis(Ct)antigen with monoclonal antibody immunogold filtration assay,and to detect mycoplasma and their drug sensitivity with culture method.Results Resistance of Uu to Tetracycline,Ofloxacin,Sparfloxacin and Levofloxacin were 27.1%,40.4%,32.0%and 34.0%,respectively.Resistance to Tetracycline,Ofloxacin,Sparfloxacin and Levofloxacin in both Uu and Mh isolate were 40.0%,60.0%,50.0%and 50.0%,respectively.Doxycycline,Josamycin,Minocycline and Clarithromycin had the higher bacteriostatic ability.Conclusion The antibiotic resistance of mycoplasma is different in vary areas,must be refereneed of antibiotic susceptibility test results before to select proper drugs for treatment.Experimental evidence showed Doxycycline,Josamycin,Minocycline and Clarithromycin can be used as the first choice for clinical medicine in mycoplasma infection.