温心汤治疗冠心病自发性心绞痛82例临床观察

采用随机单盲法观察温心汤治疗冠心病自发性心绞痛８２例之疗效。结果表明：心绞痛总有效率达９５．１２％，心电图总有效率达７４．３９％，均优于消心痛对照组４０例（Ｐ＜０．０１）。治疗后次极量运动试验运动时间由４７４．６６±９６．３３ｓ延长至５４８．８３±９９．９３ｓ，作功量由１０４．１６±１９．６５Ｗ增加至１２３．６１±２４．９６Ｗ，ＳＴ段下移值由０．１８３±０．０４１ｍＶ降至０．１３９±０．０３８ｍＶ。患者体外血栓实验血栓长度由２３．５６±５．４７ｍｍ降至２０．０４±５．１７ｍｍ，湿重由９２．６５±１８．４５ｍｇ降至７６．９４±１５．０８ｍｇ，干重由２１．７６±７．３０ｍｇ降至１６．９０±５．３５ｍｇ。提示温心汤治疗自发性心绞痛有一定疗效。

Clinical Observation of Wenxin Decoction in Treating 82 Patients with Spontaneous Angina Pectoris

One hundred twenty-two patients with spontaneous angina pectoris(SAP) were randomly divided into treated group(82 cases) and control group(40 cases),and treated with Wenxin decoction and isosorbide dinitrate respectively.Results showed that in treated group the total effective rate of SAP was 95.12% and that of electrocardiographic findings were 74.39%.These results were all superior to those of control group(P<0.01).Moreover, results of extracorporeal thrombosis test showed after Wenxin decoction treatment,the length of thrombus decreased from 23.56±5.47 mm to 20.04±5.17mm,the wet weight of it decreased from 92.65±18.45mg to 76.94±15.08 mg and the dry weight from 21.76±7.30 mg to 16.90±5.35mg. The submaximal exercise test revealed an increase of exercise time from 474.66±96.33 seconds to 548.83±99.93 seconds,increase of acting quantity from 104.16±19.65 W to 123.61±24.96 W and a decrease of ST segment depression from 0.183±0.041mV to 0.139±0.038mV.These results suggested that Wenxin decoction is valuable in treating SAP.