针刺对2型糖尿病大鼠胰岛素抵抗影响的实验研究

[目的】探讨针刺对2型糖尿病胰岛素抵抗的作用机制。[方法】采用2型糖尿病(NIDDM)大鼠模型，分为两组，观察组10只，以针刺治疗，取穴：中脘、曲池、合谷、足三里等。对照组10只，不做治疗。[结果]针刺后，2型糖尿病大鼠血糖明显下降。胰岛素敏感指数明显升高，外周组织对葡萄糖的摄取显著增加。两组相比较，有显著性差异（P＜0.01，P＜0.05）。[结论]针刺能使2型糖尿病大鼠胰岛素抵抗逆转或减轻。

Effect of Acupuncture on Insulin Resistance in Rats with Type 2 Diabetes

Objective To explore the effective mechanism of acupuncture on insulin resistance in rats with type 2 diabetes. [Methods] Rats with type 2 diabetes were selected and randomly divided into two groups: treatment group (10 rats)with acupuncture therapy,using Zhongwan,Quchi,Hegu,Zusanli etc. as the acupoints; control group (10 rats) without any treatment. [Results] Blood sugar of rats with type 2 diabetes was decreased after acupuncture apparently,and insulin sensitivity index was increased markedly. Intaking rate of glucose in peripheral tissue was enhanced apparently. There was significantly difference between two groups(P<0.01,P< 0.05).[Conclusion] Acupuncture can ameliorate or reverse the insulin resistance of rats with type 2 diabetes.