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克汀病患者垂体甲状腺轴功能的研究
引用本文:苏天水,欧阳安,Hershman J.M,张保田,郝康太. 克汀病患者垂体甲状腺轴功能的研究[J]. 中国地方病学杂志, 1987, 0(4)
作者姓名:苏天水  欧阳安  Hershman J.M  张保田  郝康太
作者单位:河南省医学科学研究所内分泌研究室,河南省医学科学研究所内分泌研究室,美国加州大学洛杉矶分校医学院内分泌科,洛阳地方病防治研究所,方城县卫生防疫站 主任
摘    要:
本文测定了两个病区共53名克汀病患者的血清中促甲状腺激素、甲状腺激素及甲状腺球蛋白浓度。同时选非病区53名正常人做对照。两病区患者所测指标水平大部分在正常范围内。表明缺碘原因所致的克汀病经补碘后,缺碘状态可以改善,垂体甲状腺激素可恢复正常水平。

关 键 词:克汀病  垂体甲状腺轴

A STUDY ON FUNCTION OF PITUITARY THYROID AXIS IN ENDEMIC CRETINISM
Su Tianshui. A STUDY ON FUNCTION OF PITUITARY THYROID AXIS IN ENDEMIC CRETINISM[J]. Chinese Jouranl of Endemiology, 1987, 0(4)
Authors:Su Tianshui
Affiliation:Su Tianshui
Abstract:
The concentration of serum T_4,T_3,T_3B,FT_3,FT_4 TSH and Thyroglobulin (Tg)in 53 normals,31 endemic cretinism of Fangchen county and 20 of Luan-chuang county was measured by immunoradiometric assay(IRMA)and radio-immunoassay(RIA)respectively.The mean levels of serum TSH,T_3,FT_3and Tg in Fangchen county were higher than that of control group.The FT_4was lower than that of the control group.The result of hormone measuremen-ts was in the normal range in the greater part of subjects.It was showed thatthe function of the pituitary-thyroid axis in these endemic cretinisms couldbe converted into normal after adminstration of iodised salt.
Keywords:Endemic cretinism  pituitary thyroid axis
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