正五聚蛋白3与脑缺血

正五聚蛋白(pentraxin, PTX)3是一类长链 PTX,作为一种炎性标记物,其血浆水平在动脉粥样硬化、心血管疾病、感染、炎症、自身免疫性疾病或组织损伤等情况下升高。最近的研究显示,血浆 PTX3水平在缺血性脑血管病急性期迅速升高。检测血浆 PTX3水平可能有助于急性脑梗死的诊断、治疗和预后判断。

Pentraxin 3 and cerebral ischemia

Pentraxin (PTX) 3 is a typical long PTX. As an inflammatory marker, the plasma PTX3 level is elevated in atherosclerosis, cardiovascular disease, infection, inflammation, autoimmune disease and tissue injury. Recently studies have shown that the plasma PTX3 level rapidly increased during the acute phase of ischemic cerebrovascular disease. Detection of plasma PTX3 level may be contribute to the diagnosis, treatment and prognostic judgment of acute cerebral infarction.