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轻度认知损害患者的静息态功能磁共振成像
引用本文:滕振杰,张丹丹,吕佩源. 轻度认知损害患者的静息态功能磁共振成像[J]. 国际脑血管病杂志, 2016, 0(4): 366-370. DOI: 10.3760/cma.j.issn.1673-4165.2016.04.011
作者姓名:滕振杰  张丹丹  吕佩源
作者单位:1. 河北医科大学研究生学院, 石家庄,050017;2. 050017 石家庄,河北医科大学研究生学院;050051 石家庄,河北省人民医院神经内科
基金项目:河北省科技支撑计划项目(14277787D),河北省自然科学基金(H2013307046)Science & Technology Pillar Program of Hebei Province of China(14277787D),Natural Science Foundation of Hebei Province of China(H2013307046)
摘    要:识别轻度认知损害(mild cognitive impairment,MCI)的意义在于能尽早进行干预并推迟甚至阻止其进展为痴呆.不过,由于受到诊断方法和标准的限制,MCI患者的诊断较为困难.近年来,静息态功能磁共振成像(resting-state functional magnetic resonance imaging,rs-fMRI)作为一种新兴的功能影像学技术得到迅速发展,被广泛应用于MCI的研究,有可能为MCI的诊断提供客观的生物学标记物.文章就rs-fMRI在MCI中的研究进展进行了综述.

关 键 词:认知障碍  轻度认知障碍  阿尔茨海默病  脑血管障碍  磁共振成像  图像处理,计算机辅助

Resting-state functional magnetic resonance imaging in patients with mild cognitive impairment
Abstract:The significance of identification of mild cognitive impairment (MCI) is to intervene as soon as possible and delay or even prevent its progression to dementia.However,due to the limitations of diagnostic methods and standards,the diagnosis of in patients with MCI is more difficult.In recent years,as an emerging functional neuroimaging technique,resting-state functional magnetic resonance imaging (rsfMRI) has developed rapidly.It has been widely used in the studies of MCI.It may be provide objective biomarkers for the diagnosis of MCI.This article reviews the advances in research on rs-fMRI in MCI.
Keywords:Cognition Disorders  Mild Cognitive Impairment  Alzheimer Disease  Cerebrovascular Disorders  Magnetic Resonance Imaging  Image Processing,Computer-Assisted
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