235例胆道感染病原菌组成及其耐药性分析

目的:了解胆道感染的病原菌组成及耐药现状,为临床医师合理使用抗菌药物提供依据。方法:对235例胆道感染患者的胆汁进行细菌培养鉴定及药敏分析。结果:胆汁病原菌检出率为61.7%,其中革兰阴性杆菌占59.3%,革兰阳性球菌占38.9%,假丝酵母菌占1.8%。细菌构成比中,前4位病原菌分别为肠球菌属37.7%、大肠埃希菌29.3%、克雷伯菌属18.6%、铜绿假单胞菌5.4%。主要革兰阴性杆菌对亚胺培南和阿米卡星敏感,肠球菌属对万古霉素、氯霉素、氨苄青霉素、青霉素、高浓度庆大霉素敏感。产超广谱β-内酰胺酶的大肠埃希菌和克雷伯菌属共检出30株,产酶率为37.5%。结论:胆汁细菌培养与药敏分析可为临床合理应用抗菌药物提供依据。

Composition of Pathogenic Bacteria and Drug Resistance in Biliary Tract Infection:Analysis of 235 Cases

OBJECTIVE:To study the composition of pathogenic bacteria and drug resistance in biliary tract infection for clinicians' reference about rational application of antibiotics. METHODS:Bacteria culture and drug susceptibility analysis were performed for the bile samples of 235 cases. RESULTS:The detection rate of pathogenic bacteria in bile was 61.7%,with gram-negative bacilli representing 59.3%,gram-positive bacilli 38.9% and Candida mycoderma 1.8%. With regard to constituent ratios of the bacteria,leading th...