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血清降钙素原水平检测在脓毒症患者中的临床意义
引用本文:唐艳,刘翠兰,李娜. 血清降钙素原水平检测在脓毒症患者中的临床意义[J]. 中国医药指南, 2012, 0(29): 426-427
作者姓名:唐艳  刘翠兰  李娜
作者单位:邵阳市中心医院检验科,湖南邵阳422000
摘    要:
目的探讨脓毒症患者检测血清降钙素原水平的临床意义。方法收集脓毒症患者100例入脓毒症组及健康体检成年人80例为对照组,检测脓毒症组和对照组血清降钙素原水平。脓毒症患者予以Sepsis集束化治疗及乌司他丁治疗。检测治疗前及治疗后PCT、CRP水平,及APACHEⅡ评分,探讨PCT水平变化及其与APACHEⅡ评分的关系,探讨不同预后患者PCT水平的差异。结果脓毒症患者血清PCT水平明显高于对照组(P<0.01),且随着治疗进展血浆PCT水平逐渐降低(P<0.01)。死亡患者PCT水平明显高于存活患者(P<0.05)且PCT与APACHEⅡ评分呈正相关(P<0.05)。结论血浆PCT水平对脓毒症患者的诊断及严重程度评价有重要价值。

关 键 词:脓毒症  降钙素原

The Clinical Significance of Serum Procalcitonin Levels Detected in Patients with Sepsis
TANG Yan,LIU Cui-lan,LI Na. The Clinical Significance of Serum Procalcitonin Levels Detected in Patients with Sepsis[J]. Guide of China Medicine, 2012, 0(29): 426-427
Authors:TANG Yan  LIU Cui-lan  LI Na
Affiliation:(Department of Laboratory,Shaoyang Central Hospital,Shaoyang 422000,China)
Abstract:
Objective To study the clinical significance of PCT in patients with sepsis.Methods 100 patients with sepsis and 80 healthy volunteers were included into the study.PCT levels were studied in sepsis patients and 80 control subjects.All the patients received routine treatment,additionally treated with ulinastatin.The PCT,CRP,APACHE-Ⅱ values were detected before treatment and after treatment.The relationship between the PCT,and APACHEⅡwere studied.Results The PCT levels of Sepsis were significantly higher than control subjects(P0.01).PCT level was gradually decreasing after treatment(P0.05).The APACHE-Ⅱ values were significantly decreased after treatment(P0.05).The PCT levels was significant positive correlation with APACHE-Ⅱ(P 0.05).Conclusion PCT may has a significant predictive value on sepsis severity.
Keywords:Sepsis  PCT
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