| 烧伤病区多重耐药铜绿假单胞菌DNA的脉冲场凝胶电泳分析 |
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| 引用本文： | 蒋伟,常东,雷树红,商振涛.烧伤病区多重耐药铜绿假单胞菌DNA的脉冲场凝胶电泳分析[J].感染、炎症、修复,2006,7(3):164-166. |
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| 作者姓名： | 蒋伟 常东 雷树红 商振涛 |
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| 作者单位： | 100037,北京,解放军总医院第一附属医院检验科 |
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| 摘 要： | 目的:了解烧伤病区铜绿假单胞菌(Pseudomonas aeruginosa,PA)感染的分子流行病学特征。方法:采用脉冲场凝胶电泳(PFGE)分型的方法,对15株分离自烧伤临床病人的多重耐药PA染色体组DNA进行分析。结果:15株检测菌株中有9株菌分别属于两种不同的PFGE图谱类型,具有同源性的菌株占测试菌株的60%。结论:导致我院烧伤患者感染多重耐药的PA中有同源性的比例较高,提示在烧伤救治中采取有针对性的措施,防止烧伤病房内的交叉感染对于降低烧伤感染率、提高烧伤救治水平具有重要意义。
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| 关 键 词： | 铜绿假单胞菌 脉冲场凝胶电泳 分子流行病学 烧伤 |
Study on molecular epidemiology of multi-resistant Pseudomonas aeruginosa isolated from burn unit by pulsed-field gel electrophoresis |
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| Jiang Wei,Chang Dong,Lei shuhong,et al..Study on molecular epidemiology of multi-resistant Pseudomonas aeruginosa isolated from burn unit by pulsed-field gel electrophoresis[J].Infection Inflammation Repair,2006,7(3):164-166. |
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| Authors: | Jiang Wei Chang Dong Lei shuhong |
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| Institution: | Jiang Wei,Chang Dong,Lei shuhong,et al. Department of laboratory Medicine,The First Affiliated Hospital of PLA General Hosporal,Beijing,100037 |
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| Abstract: | Object: To investingate the molecular epidemiology of Pseudomonas aeruginosa isolated from burn wounas. Methods: Fifteen multi-resistant P. aeruginosa strains were isolated from clinical specimens obtained from a burn unit. Pulsed-field gel electrophoresis (PFGE) was used to type the chromosome DNA of the strains. Results: Two PFGE patterns were found among 9 strains and 60 of strains were homologs. Conclusions: The results suggested that the prevention of cross-infection in burn unit might be a key factor in decreasing the incidence of burn infection and improving the curative effect of burn injury. |
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| Keywords: | Pseudomonas aeruginosa Pulsed-field gel electrophoresis Molecular epidemiology Burns |
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