| 首发抑郁症患者糖脂代谢研究 |
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| 引用本文： | 夏青春,王高华,王惠玲,谢志兵,方悦,李烨.首发抑郁症患者糖脂代谢研究[J].临床精神医学杂志,2009,19(4). |
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| 作者姓名： | 夏青春 王高华 王惠玲 谢志兵 方悦 李烨 |
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| 作者单位： | 精神科,武汉大学人民医院,426200 |
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| 摘 要： | 目的:探讨首发抑郁症患者的糖脂代谢情况。方法:对80例首发抑郁症患者及40名健康对照者先进行简易体脂参数的测量,然后进行糖耐量试验(OGTT),并检测其空腹血浆胰岛素、三酰甘油(TG)、总胆固醇(TC)的浓度。结果:体脂参数、空腹血浆胰岛素的浓度、餐后0、1、3h血糖值,两组间差异均无显著统计学意义(P均>0.05);抑郁症组空腹血糖值(FBS)、餐后2h的血糖值、OGTT血糖曲线下面积(AUC)、TG值明显高于对照组(P<0.01);而高密度脂蛋白(HDL-c)、载脂蛋白A1(ApoA1)值抑郁症组明显低于对照组(P<0.01),TC、低密度脂蛋白胆固醇(LDL-c)和载脂蛋白B(ApoB)值两组间差异均无统计学意义(P均>0.05);两组糖耐量减退(IGT)的发生率差异有统计学意义(P<0.05),抑郁症组IGT发生率较对照组高。结论:首发抑郁症患者存在一定的糖脂代谢异常,临床医师应该对抑郁症患者的血糖、血脂进行随访监测,以便早期发现、治疗糖脂代谢性疾病。
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| 关 键 词： | 首发抑郁症 血糖 血脂 糖耐量 |
Study of metabolism of glucose and lipid in patients with first-episode depression |
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| XIA Qin-chun,WANG Gao-hua,WANG Hui-ling,XIE Zhi-bin,FANG Yue,LI Ye.Study of metabolism of glucose and lipid in patients with first-episode depression[J].Journal of Clinical Psychological Medicine,2009,19(4). |
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| Authors: | XIA Qin-chun WANG Gao-hua WANG Hui-ling XIE Zhi-bin FANG Yue LI Ye |
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| Institution: | XIA Qin-chun,WANG Gao-hua,WANG Hui-ling,XIE Zhi-bin,FANG Yue,LI Ye.Department of Psychiatry,People's Hospital of Wuhan University,Wuhan 426200,China |
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| Abstract: | Objective:To study the metabolism of glucose and lipid in patients with first-episode depression.Method:Parameters such as body weight index and lipid were measured in 80 patients with first-episode depression and 40 healthy controls.All the patients and controls were conducted oral glucose tolerance test(OGTT),and their fasting plasma concentration of insulin,triglyceride(TG)and cholesterol were measured.Results:There was no significance between the two groups in parameters of body weight index and lipid,f... |
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| Keywords: | first-episode depression glucose lipid glucose tolerance |
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