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人巨细胞病毒感染与炎症性肠病的相关研究进展
引用本文:吉阳,黎锐平,王明丽. 人巨细胞病毒感染与炎症性肠病的相关研究进展[J]. 世界华人消化杂志, 2012, 0(22): 2070-2074
作者姓名:吉阳  黎锐平  王明丽
作者单位:安徽医科大学基础医学院微生物学教研室;安徽中医学院附属医院内镜中心
基金项目:安徽省科技厅科技攻关基金资助项目,No.08010302179~~
摘    要:
人巨细胞病毒(human cytomegalo virus,HCMV)是普遍存在的DNA病毒,在免疫损伤或免疫抑制的患者中常导致严重疾病.已有研究发现,HCMV在炎症性肠病(inflammatory boweldisease,IBD)的发生和发展中起一定作用.本文综述了近年来有关IBD患者中HCMV感染的临床调查和临床诊断方法,并初步探讨了HCMV感染与IBD发生的相关机制.

关 键 词:炎症性肠病  人巨细胞病毒  免疫抑制

Progress in understanding the relationship between inflammatory bowel disease and human cytomegalovirus infection
Yang Ji,Ming-Li Wang. Progress in understanding the relationship between inflammatory bowel disease and human cytomegalovirus infection[J]. World Chinese Journal of Digestology, 2012, 0(22): 2070-2074
Authors:Yang Ji  Ming-Li Wang
Affiliation:,Department of Microbiology,Anhui Medical University,Hefei 230032,Anhui Province,China Rui-Ping Li,Center for Endoscopy,Anhui University of Traditional Chinese Medicine,Hefei 230032,Anhui Province,China
Abstract:
Human cytomegalovirus(HCMV) is a ubiquitous DNA virus that can cause severe disease in immunosuppressive or immunocompromised patients.Recent studies have found that CMV might play a role in the pathogenesis and progression of inflammatory bowel disease(IBD).This paper gives a review of the epidemiology,clinical diagnosis,and pathogenesis of HCMV infection in patients with IBD.
Keywords:Inflammatory bowel disease  Human cytomegalovirus  Immunosuppression
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