慢性阻塞性肺疾病与肺外相关疾病的研究进展

慢性阻塞性肺疾病(COPD)是一种以气流受限不完全可逆为特征的可以预防和治疗的疾病,主要累及肺脏,但也可以引起全身(或肺外)的不良反应。2009年版GOLD(慢性阻塞性肺疾病全球倡议)强调每例患者临床病情取决于症状严重程度、全身效应和各种合并症,而并非仅仅与气流受限程度相关。对COPD的阐述更注重肺外效应与患者疾病严重程度的相关性,在COPD的临床管理中也更关注对其肺外效应和合并症的处理。

Research Progress in COPD and Extrapulmonary Related Diseases

Chronic obstructive pulmonary disease(COPD)is a disease characterized by less reversible airflow limitation,which can be prevented and treated.COPD mainly involves the lungs,but can also cause systemic(extrapulmonary)adverse reactions.The 2009 GOLD(Global Initiative for Chronic Obstructive Pulmonary Disease)stressed that the individual clinical condition depends on the severity of symptoms,systemic effect and variety of complications,not only the degree of airflow limitation.More emphasis is on the correlation of the disease and extrapulmonary effect,while in the clinical management of COPD,there are also more concerns about the treatment of extrapulmonary effects and pulmonary complications.