活血解毒方降血糖作用的实验研究

目的:观察活血解毒方对实验性糖尿病大鼠的降血糖作用。方法:对大鼠一次性腹腔注射链脲佐菌素(Streptozocin,STZ)30mg.kg-1建立糖尿病(diabetes mellitus,DM)模型,将建模成功的大鼠随机分为6组,另设正常对照组,连续给药30d,在相应时间点测随机血糖、体重、做糖耐量试验。结果:灌服活血解毒方各剂量组的血糖明显低于模型组;活血解毒方减缓糖尿病大鼠体重下降,对糖耐量具有显著的改善作用。结论:活血解毒方的降血糖作用比较显著。

Empirical Study of Effect of Huoxuejiedu Decoction Reducing Blood Sugar

Objective：To observe the effect of Huoxuejiedu Decoction on reducing blood sugar function of rats suffering from diabetes mellitus by experiences.Methods：Rats were injected 30mg/kg without a second time by using strepozocin（STZ） to establish rat model of diabetes mellitus and were randomly divided into six groups,additionally establishing the control group,continully infusing rats with drugs 30days,gauging random blood sugar,measuring weight and doing glucose tolerance test.Results：The blood sugar density of rat＇s which were infused with respective dose of HXJD Decoction group was significantly lower than that of diabetes mellitus of model group（P﹤0.05）.HXJD Decoction group can not only slow down the drop of diabetic rats＇weight,but also obviously improve their glucose tolerance＇s capacities.