Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Acetaldehyde inhibits PPARgamma via H2O2-mediated c-Abl activation in human hepatic stellate cells

Authors:	Ceni Elisabetta Crabb David W Foschi Marco Mello Tommaso Tarocchi Mirko Patussi Valentino Moraldi Luca Moretti Renato Milani Stefano Surrenti Calogero Galli Andrea

Affiliation:	Gastroenterology Unit, Department of Clinical Pathophysiology, University of Florence, Viale Morgagni 85, 50134 Florence, Italy.

Abstract:

Keywords:	AcCHO, acetaldehyde DMSO, dimethyl sulfoxide ERK, extracellular signal-regulated kinase HSC, hepatic stellate cell JNK, c-Jun-N-terminal kinase MAP, mitogen-activated protein MEK, mitogen-activated protein kinase kinase MOI, multiplicity of infection PEG-CAT, polyethylene glycol-conjugated catalase PKC, protein kinase C PPAR, peroxisome proliferator-activated receptor PPRE, peroxisome proliferator response element RGZ, rosiglitazone siRNA, small interfering RNA SDS-PAGE, sodium dodecyl sulfate/polyacrylamide gel electrophoresis SFIF, serum-free/insulin-free medium TGF, transforming growth factor wt, wild-type
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