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Particle Aerosolisation and Break-up in Dry Powder Inhalers 1: Evaluation and Modelling of Venturi Effects for Agglomerated Systems
Authors:William Wong  David F. Fletcher  Daniela Traini  Hak-Kim Chan  John Crapper  Paul M. Young
Affiliation:(1) Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney, Sydney, NSW, 2006, Australia;(2) School of Chemical and Biomolecular Engineering, University of Sydney, Sydney, NSW, 2006, Australia;(3) Pharmaxis Ltd., Unit 2, 10 Rodborough Rd, Frenchs Forest, Sydney, NSW, 2086, Australia;
Abstract:

Purpose  

This study utilized a combination of computational fluid dynamics (CFD) and standardized entrainment tubes to investigate the influence of turbulence on the break-up and aerosol performance of a model inhalation formulation.
Keywords:
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