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糖肾康方治疗Ⅳ期糖尿病肾病40例疗效观察
引用本文:徐成兴,胡蕴刚.糖肾康方治疗Ⅳ期糖尿病肾病40例疗效观察[J].上海中医药杂志,2005,39(5):22-24.
作者姓名:徐成兴  胡蕴刚
作者单位:上海市南汇区中心医院,上海,201300;上海市南汇区中心医院,上海,201300
摘    要:为观察自拟糖肾康方治疗糖尿病肾病(DN)的临床疗效,将80例患者随机分为治疗组和对照组各40例,对照组采用西医常规治疗,治疗组在此基础上加用中药糖肾康方治疗。结果:治疗组总有效率为85%,对照组为60%,治疗组明显优于对照组(P<0 .05);治疗组治疗前后空腹血糖、餐后2小时血糖、糖化血红蛋白、血清肌酐、血尿素氮、24小时尿蛋白定量、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白等变化差异有显著性(P<0. 05或P<0. 01),TG、24小时尿蛋白定量, 2组治疗后比较,有显著性差异(P<0 .05)。结论:糖肾康方结合西医常规治疗糖尿病肾病效果优于单纯西医治疗。

关 键 词:糖尿病肾病  随机对照试验  中西医结合疗法  糖肾康方
文章编号:1007-1334(2005)05-0022-03
修稿时间:2005年3月12日

Clinical Observation of "Tangshengkang Decoction" in Treating Phase Four Diabetic Nephropathy in 40 Cases
XU Cheng-xing,HU Yun-gang.Clinical Observation of "Tangshengkang Decoction" in Treating Phase Four Diabetic Nephropathy in 40 Cases[J].Shanghai Journal of Traditional Chinese Medicine,2005,39(5):22-24.
Authors:XU Cheng-xing  HU Yun-gang
Abstract:To observe the clinical efficacy of self-composed "Tangsheng kang Decoction" in the treatment of diabetic nephropathy, 80 subjects were equa lly randomized into control group and treatment group, and then treated respecti vely by western routine and integrative Chinese and western medications. Results : The total effective rate was 85.0% in treatment group and 60 0% in control gr oup, P<0.05; after treatment, FPG, 2hPG, HbAlC, TG, 24hUP and other indexes improved obviously in treatment group (P<0.05, P<0.01), with significant improvement in TG and 24hUP compared to control group (P<0 05). Conclusion : "Tangshengkang Decoction" plus western medication has better effects than si mple western medication in treating diabetic nephropathy.
Keywords:Diabetic nephropathy  randomized controlled trial  integrative  Chinese and western medicine  "Tangshengkang Decoction"
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