Dynamic contrast-enhanced magnetic resonance imaging of the sarcopenic muscle |
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| Authors: | Elena?Nicolato Paolo?Farace Roberto?M?Asperio Pasquina?Marzola Ernesto?Lunati Andrea?SbarbatiEmail author Francesco?Osculati |
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| Affiliation: | Dipartimento di Scienze Morfologico-Biomediche, Sezione di Anatomia ed Istologia, Università di Verona, Verona, I-37194, Italy. sbarbati@borgoroma.univr.it |
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| Abstract: | Background Studies about capillarity of the aged muscle provided conflicting results and no data are currently available about the magnetic resonance imaging (MRI) in vivo characteristics of the microvascular bed in aged rats. We have studied age-related modifications of the skeletal muscle by in vivo T2-relaxometry and dynamic contrast-enhanced magnetic resonance imaging (CE-MRI) at high field intensity (4.7 T). The aim of the work was to test the hypothesis that the ageing process involves microvessels in skeletal muscle. |
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