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参麦注射液联合化疗治疗中晚期非小细胞肺癌临床观察
引用本文:郭志峰,韩建国,杨艳,孔凡龙,王小林.参麦注射液联合化疗治疗中晚期非小细胞肺癌临床观察[J].内蒙古医学杂志,2010,42(10):1179-1181.
作者姓名:郭志峰  韩建国  杨艳  孔凡龙  王小林
作者单位:赤峰市医院肿瘤内二科,内蒙古赤峰024000
摘    要:目的:评价参麦注射液联合紫杉醇(PTX)加顺铂(PDD)组成的TP方案全身化疗治疗中晚期非小细胞肺癌(NSCLC)的疗效和毒副反应。方法:将62例晚期NSCLC患者随机分为治疗组31例和对照组31例,分别接受TP方案加参麦注射液或单纯TP方案化疗。结果:治疗组有效率51.61%高于对照组有效率48.39%,差异无统计学意义(P〉0.05);治疗组毒性反应低于对照组(P〈0.05)。治疗组生活质量明显改善(P〈0.05)。结论:参麦注射液配合TP方案化疗在治疗非小细胞肺癌中可提高化疗疗效,减轻化疗毒性,提高患者生活质量。

关 键 词:参麦注射液  非小细胞肺癌  紫杉醇  顺铂

The Clinical Observation of Advanced Non small Cell Lung Cancer Treated with ShenMai Injection Combined with the Chemotherapy
GUO Zhi-feng,HAN Jian-guo,YANG Yan,KONG Fan-long,WANG Xiao-lin.The Clinical Observation of Advanced Non small Cell Lung Cancer Treated with ShenMai Injection Combined with the Chemotherapy[J].Inner Mongolia Medical Journal,2010,42(10):1179-1181.
Authors:GUO Zhi-feng  HAN Jian-guo  YANG Yan  KONG Fan-long  WANG Xiao-lin
Institution:(The Hospital of Chifeng City,Chifeng 024000 China)
Abstract:Objective:To evaluate the efficacy of combination ShenMai injection with PTX and DDP chemotherapy(TP regimen)for the treatment of advanced non-small cell lung cancer(NSCLC).Methods:62 patients were devided into control group(ShenMai injection combined with chemotherapy,31 cases)and treatment group(chemotherapy alone,31 cases) randomly.Results:The overall response rate of treatment group and control group were 51.61% and 48.39% respectively,there was no significant difference between the two group(P〈0.05);The life quality and relieved chemotherapy toxity of patients in treatment group were superior to the patients in control group(P〈0.05).Conclusion:ShenMai injections can improve the curative effect of advanced non-small cell lung cancer,decrease toxic reaction and improve quality of life for advanced NSCLC.
Keywords:ShenMai injections  Advanced non-small cell lung cancer  PTX  DDP
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