我国儿童合理用药的文献研究计量学分析

目的 为进一步促进我国儿童合理用药研究提供建议。方法 运用文献计量学和可视化的方法，采用数据挖掘、信息抽取、关键词共现分析等技术，对知网、万方、维普三大数据库收录的2013—2017年我国儿童合理用药的相关文献进行分析。结果 共检索到相关文献14 948篇；从期刊分布来看，文献分布比较广泛，说明儿童合理用药问题受到社会各界的广泛关注；从作者单位分布来看，文献主要来自各儿童医院、妇幼保健院及综合医院，尤其是大学的附属医院是我国儿童合理用药研究的主要力量；由选用的高频关键词看出，我国儿童合理用药的研究热点为抗菌药物或抗生素、糖皮质激素、超说明书用药等方面。结论 虽然文献总量很大，但多为对单个医院单因素儿童用药干预前后对比的研究，多地区、多层次、大样本的合理用药研究较少，研究缺乏系统性，研究的广度和深度还有所欠缺。

Bibliometric analysis of literature on rational use of medicine in children of China

Objective To provide advice to further promote the rational use of drugs in children.Methods Bibliometric and visualization methods were used through data mining,information extraction,keyword co-occurrence analysis and other techniques to analyze the relevant literature on the rational use of drugs in China from 2013 to 2017 including the three databases of China National Knowledge Internet,Wanfang and Weipu Analyze.Results A total of 14 948 articles were retrieved from the three databases.From the perspective of journal distribution,the literature distribution was quite extensive,indicating that children''s rational drug use had received wide attention from all walks of life.From the distribution of authors,the literature mainly came from children''s hospitals,maternal and child health centers and comprehensive hospitals,especially affiliated hospitals of universities,which were the main force for the rational use of drugs in children in China.The high-frequency keywords used in the study indicate that the research hotspots of rational use of drugs in China were antibiotics,glucocorticoids,and super-indicative drugs.Conclusion The total amount of literature was very large,but most of them were comparative studies before and after single-factor children''s drug intervention in a single hospital.There were few studies on rational drug use in multi-region,multi-level and large-scale samples.The lack of systematic research,the breadth and depth of research was not enough.