CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea |
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Authors: | Gwack J Shin A Kim C-S Ko K-P Kim Y Jun J K Bae J Park S K Hong Y-C Kang D Chang S-H Shin H-R Yoo K-Y |
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Affiliation: | Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-799, Korea. |
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Abstract: | In a nested-case control study of 100 cases of gastric cancer and 400 matched controls in relation to virulence factors of Helicobacter pylori in a Korean cohort, CagA seropositivity was significantly associated with a higher risk of gastric cancer among H. pylori-infected subjects (OR=3.57, 95% CI 1.05-12.14). |
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Keywords: | gastric cancer Helicobacter pylori CagA Cohort study Korea |
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