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CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea
Authors:Gwack J  Shin A  Kim C-S  Ko K-P  Kim Y  Jun J K  Bae J  Park S K  Hong Y-C  Kang D  Chang S-H  Shin H-R  Yoo K-Y
Affiliation:Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110-799, Korea.
Abstract:
In a nested-case control study of 100 cases of gastric cancer and 400 matched controls in relation to virulence factors of Helicobacter pylori in a Korean cohort, CagA seropositivity was significantly associated with a higher risk of gastric cancer among H. pylori-infected subjects (OR=3.57, 95% CI 1.05-12.14).
Keywords:gastric cancer   Helicobacter pylori   CagA   Cohort study   Korea
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